Quest for Biomarkers of Treatment-Resistant Depression: Shifting the Paradigm Toward Risk
نویسندگان
چکیده
منابع مشابه
Quest for Biomarkers of Treatment-Resistant Depression: Shifting the Paradigm Toward Risk
The search for potential biomarkers of psychiatric disorders is a central topic in biological psychiatry. This review concerns published studies on potential biomarkers of treatment-resistant depression (TRD). The search for biomarkers of TRD in the bloodstream has focused on cytokines and steroids as well as brain-derived neurotropic factor. Additional approaches to identifying biomarkers of T...
متن کامل“the effect of risk aversion on the demand for life insurance: the case of iranian life insurance market”
abstract: about 60% of total premium of insurance industry is pertained?to life policies in the world; while the life insurance total premium in iran is less than 6% of total premium in insurance industry in 2008 (sigma, no 3/2009). among the reasons that discourage the life insurance industry is the problem of adverse selection. adverse selection theory describes a situation where the inf...
15 صفحه اولPS193. MicroRNAs as biomarkers for treatment-resistant depression
s | 71 groups, only KYN correlated with SERT in the midbrain in HC (ρ=-0.544, p=0.001). A further analysis showed that, at TBI > 0.06, midbrain SERT correlated with TRP (ρ=-0.900, p=0.037), KYN (ρ=-0.900, p=0.037), and TBI (ρ=0.900, p=0.037) in HC. However, this could not be replicated in MDD. Conclusion: Our results are the first to demonstrate complicated interactions between TRP metabolism a...
متن کاملTreatment-resistant depression and risk of suicide.
We evaluated whether treatment-resistant depression (TRD) as measured by the Massachusetts General Hospital (MGH) staging method was associated with suicide in a large U.S. health system. Data from the Veterans Health Administration and the National Death Index were used to conduct a case-control study of patients newly diagnosed with depression who received antidepressant treatment between 200...
متن کاملHypertension and chronotherapy: shifting the treatment paradigm.
The treatment of diseases has been based on the concept of homeostasis and has not incorporated an understanding of biologic rhythms and their underlying mechanisms. Biologic rhythms are implicated in cardiovascular events. Failure to recognize the circadian decline in blood pressure may result in iatrogenic chronopathological events, including anterior ischemic optic neuropathy and cerebrovasc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Psychiatry
سال: 2013
ISSN: 1664-0640
DOI: 10.3389/fpsyt.2013.00057